cancertherapy相关论文
Repurposing non-oncology small-molecule drugs to improve cancer therapy:Current situation and future
Drug repurposing or repositioning has been well-known to refer to the therapeutic applications of a drug for another ind......
MicroRNAs (miRNAs) are a class of endogenously expressed non-coding regulators of the genome with an ability to mediate ......
The tumor microenvironment features over-expressed hydrogen peroxide (H2O2).Thus,versatile therapeutic strategies based ......
光动力学疗法(PDT)是一种依赖于氧气的新兴治疗手段,但是由于肿瘤部位血管供氧不足,乏氧微环境极大抑制了光动力学疗法的治疗效果.......
With high catalytic activity and stability,nanozymes have huge advantage in generating or eliminating the reactive oxyge......
Metal and amino acid (AA),as two kinds of entities,have been widely involved in biomaterials and nano-medicines.Recently......
Using bio-orthogonally catalyzed lethality strategy to generate mitochondria-targeting anti-tumor me
Synthetic lethality was proposed nearly a century ago by geneticists and recently applied to develop precision anti-canc......
Chemotherapy seeks to minimize tumor progression and increase patient survival.However,the main problem is to find a bal......
Inhibitation of Cellular Toxicity of Gold Nanorods by Surface Encapsulation of Silica Shell for Hepa
Nanotechnology,as a double-edged sword,endows gold nanoparticles(GNPs)more “power” in bioimaging and theragnostics,whe......
Ribonuclease A-assisted syntheses of carbon dots and its applications in Biological imaging and canc
Carbon dots (C-dots) enfolded by Ribonuclease A (RNase A) on the surface were synthesized via a one-step microwave-assis......
Prussian blue-based nanomaterials: the new generation of photothermal ablation agent for cancer ther
Photothermal therapy (PTT) has emerged as an increasingly attractive methodology for cancer therapy.Photothermal agents ......
The body is composed of several biophysical barriers that regulate the exchange, trafficking, and clearance of foreign m......
Stimuli-responsive self-assembling fluorescent turn-on nanodrug based on small molecular prodrug for
A myriad of drug delivery systems such as liposomes,micelles,polymers and inorganic nanoparticles(NPs)have been develope......
Truncated bFGF Peptide-medicated Active Targeting System Simultaneously Loaded with PEDF and Paclita
The ligand-mediated active targeting system is one of ideal gene delivery systems.Fibroblast growth factor receptors(FGF......
The ability of polyamine amides to bind to glutamate receptors has made them useful in studying cancer propagation [1].I......
Enhanced therapeutic efficacy with hydrophobic polyphosphoester-based nanoparticles via improved int
Self-assembled nanoparticles composed of amphiphilic block copolymers can efficiently encapsulate hydrophobic anticancer......
Precisely regulated nanoarchitecture comprised of gold nanotemplate and unimer polyion complex for s
RNA interference (RNM) mediated by small interfering RNA (siRNA) has attracted wide international attention for treatmen......
Multifunctional Magnetic Polymeric Nanoparticles: A Theranostic Platform for Multimodal Cancer Imagi
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Polycationic gene delivery system was widely used for cancer therapy.Polycations with high positive potentials exhibited......
Combination therapy,which refers to either the co-administration of multiple anticancer drugs or utilization of differen......
Photoactivated nanomaterials exhibit immense promise for biomedical applications because noninvasive light stimulus can ......
The transplatinum drugs are invalid in chemotherapy,mainly due to their high reactivity and rapid deactivation in blood ......
Protein therapeutics offers a most effective treatment for many human diseases including diabetes,cardiovascular disease......
Targeted cancer therapy is still a major challenge.Current chemothera-poetic drugs lack selectivity and are associated w......
Outer Membrane Vesicles(OMVs)released from klebsiella pneumoniae as a Candidate Cell-Specific Drug-D
Lung tumor is the leading cause of cancer death in the world and non-small cell lung cancer(NSCLC)accounts for 85%of lun......
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Introduction of an AIE fluorophore into cationic gene delivery vehicles verified the nuclear translo
Gene therapeutic approach rooted in the concept of engineering nanoparticulates as gene delivery vehicles to accommodate......
Mesoporous silica nanoparticles (MSNs) have evidenced to be an effective drug delivery system[1].It is well documented t......
Laser irradiation-induced plasma membrane activated polymeric nanoconstructs for photodynamic cancer
Low therapeutic efficacy in conventional drug delivery systems is usually attributed to the inadequate cellular uptake a......
Multidrug resistance(MDR)is a major problem in cancer chemotherapy.Directly delivering drug-loaded vehicles into the nuc......
In the past decade,nanoparticle-based drug delivery systems,such as gold nanoparticles,mesoporous silica nanoparticles(M......
Some gases such as CO,NO and H2S have remarkably therapeutic activity,especially to two most important diseases,cancer a......
A major challenge in cancer therapy is localized targeting of cancer cells for maximum therapeutic effectiveness.However......
Magnetosomes are natural crystalline particles and biomineralized by Magnetotactic bacteria(MTB).They are composed of na......
Silicon is well-known as the crusts second most abundant element on earth,only behind oxygen,providing a rich and low-co......
We have been exploiting inherent tumor properties in the delivery of anticancer therapeutic materials and aimed specific......
Poly(ethylene glycol) (PEG) with good biocompatibility and resistance to protein adsorption is the commonly used hydroph......
Targeting cancer metabolism is emerging as a successful strategy for cancer therapy [1].However,most marketed anti-metab......
Regulation of hydrophobicity of polyphosphoester based drug delivery system for enhanced cancer ther
Micelles self-assembled from amphiphilic copolymers with a hydrophilic shell and hydrophobic core are usually used for l......
The application of photodynamic therapy (PDT) in the treatment of cancer has remarkable advantages over conventional che......
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Facile Preparation of pH and Reduction Responsive PEGylated Polypeptide Nanogel for Efficient Doxoru
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Physical Interaction Induced Self-Assembly of Glycopeptide and Doxorubicin at Physiological pH as Pr
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目的 Cyclin dependent kinase 1 (CDK1) is an essential kinase that involves in a wide range of biological processes which......
MNK kinases phosphorylate the eukaryotic translation initiation factor eIF4E,which is a vital component of the translati......
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid(CD437/AHPN),which is RARγ agonist,c......
A novel monoclonal antibody,CC4,targeting a conserved epitope of CEACAMs significantly inhibits tumo
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Liposome is a kind of prospective abiotic drug delivery system for cancer treatment.Liposomes facilitate drugs accumulat......
